Detalhe da pesquisa
1.
Etrasimod as induction and maintenance therapy for ulcerative colitis (ELEVATE): two randomised, double-blind, placebo-controlled, phase 3 studies.
Lancet
; 401(10383): 1159-1171, 2023 04 08.
Artigo
Inglês
| MEDLINE | ID: mdl-36871574
2.
Ozanimod as Induction and Maintenance Therapy for Ulcerative Colitis.
N Engl J Med
; 385(14): 1280-1291, 2021 09 30.
Artigo
Inglês
| MEDLINE | ID: mdl-34587385
3.
Ozanimod Differentially Impacts Circulating Lymphocyte Subsets in Patients with Moderately to Severely Active Crohn's Disease.
Dig Dis Sci
; 2024 Apr 03.
Artigo
Inglês
| MEDLINE | ID: mdl-38568396
4.
Cardiovascular Safety of Ozanimod in Patients With Ulcerative Colitis: True North and Open-Label Extension Analyses.
Clin Gastroenterol Hepatol
; 2023 Nov 30.
Artigo
Inglês
| MEDLINE | ID: mdl-38040274
5.
Vedolizumab, Adalimumab, and Methotrexate Combination Therapy in Crohn's Disease (EXPLORER).
Clin Gastroenterol Hepatol
; 2023 Sep 22.
Artigo
Inglês
| MEDLINE | ID: mdl-37743037
6.
Is the 90-day dog study necessary for pesticide toxicity testing?
Crit Rev Toxicol
; 53(4): 207-228, 2023 04.
Artigo
Inglês
| MEDLINE | ID: mdl-37401640
7.
Towards achieving a modern science-based paradigm for agrochemical carcinogenicity assessment.
Regul Toxicol Pharmacol
; 137: 105301, 2023 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-36436696
8.
A new paradigm for regulatory sciences.
Regul Toxicol Pharmacol
; 145: 105524, 2023 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-37925098
9.
A new approach to the classification of carcinogenicity.
Arch Toxicol
; 96(9): 2419-2428, 2022 09.
Artigo
Inglês
| MEDLINE | ID: mdl-35701604
10.
Rethinking chronic toxicity and carcinogenicity assessment for agrochemicals project (ReCAAP): A reporting framework to support a weight of evidence safety assessment without long-term rodent bioassays.
Regul Toxicol Pharmacol
; 131: 105160, 2022 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-35311659
11.
Paraquat pharmacokinetics in primates and extrapolation to humans.
Toxicol Appl Pharmacol
; 417: 115463, 2021 04 15.
Artigo
Inglês
| MEDLINE | ID: mdl-33631232
12.
Integration of paraquat pharmacokinetic data across species using PBPK modelling.
Toxicol Appl Pharmacol
; 417: 115462, 2021 04 15.
Artigo
Inglês
| MEDLINE | ID: mdl-33631233
13.
The codification of hazard and its impact on the hazard versus risk controversy.
Arch Toxicol
; 95(11): 3611-3621, 2021 11.
Artigo
Inglês
| MEDLINE | ID: mdl-34559250
14.
Metabolomic Profiles in the Brains of Juvenile Steelhead (Oncorhynchus mykiss) Following Bifenthrin Treatment.
Environ Sci Technol
; 54(19): 12245-12253, 2020 10 06.
Artigo
Inglês
| MEDLINE | ID: mdl-32900186
15.
An evaluation framework for new approach methodologies (NAMs) for human health safety assessment.
Regul Toxicol Pharmacol
; 112: 104592, 2020 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-32017962
16.
A comprehensive view on mechanistic approaches for cancer risk assessment of non-genotoxic agrochemicals.
Regul Toxicol Pharmacol
; 118: 104789, 2020 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-33035627
17.
Ozanimod Induction and Maintenance Treatment for Ulcerative Colitis.
N Engl J Med
; 374(18): 1754-62, 2016 May 05.
Artigo
Inglês
| MEDLINE | ID: mdl-27144850
18.
Efficacy of Ustekinumab for Inducing Endoscopic Healing in Patients With Crohn's Disease.
Gastroenterology
; 155(4): 1045-1058, 2018 10.
Artigo
Inglês
| MEDLINE | ID: mdl-29909019
19.
A simple problem formulation framework to create the right solution to the right problem.
Regul Toxicol Pharmacol
; 101: 187-193, 2019 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-30513358
20.
Chemical carcinogenicity revisited 1: A unified theory of carcinogenicity based on contemporary knowledge.
Regul Toxicol Pharmacol
; 103: 86-92, 2019 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-30634023